Guides
Background reading for patients, caregivers and clinicians who source specialty medicines internationally. Each guide is compiled from public regulatory sources and links to the medication pages it discusses.
Biosimilars and originator biologics: what the difference is and what to specify
How a biosimilar differs from a generic, how the EMA approves one, what interchangeability and substitution mean in practice, and which biosimilars of adalimumab, infliximab, bevacizumab and insulin lispro exist.
Read the guideCFTR modulators in cystic fibrosis: potentiators, correctors and who they are for
How ivacaftor, lumacaftor/ivacaftor and the newer combinations act on the CFTR protein, which mutations and ages they are approved for, the interactions and monitoring that apply, and how they are stored and sourced.
Read the guideCold-chain shipping for medicines: what 2–8 °C really means
Which medicines must stay refrigerated, why freezing is as harmful as heat, how a refrigerated parcel is built, and how long each product may spend at room temperature according to its product information.
Read the guideGLP-1 receptor agonists and tirzepatide: an overview of the class
How semaglutide, liraglutide, dulaglutide and tirzepatide work, what they are approved for, how often they are injected, how they are stored, and the warnings that apply to the whole class.
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